Module V: Early Pregnancy Loss Management
Module Review Information
The resources in this module were reviewed by Sarah Prager, MD, MAS, and Robin Wallace, MD, MAS, in Spring 2025.
Learning Objectives
- Evaluate and diagnose abnormal pregnancy (anembryonic gestation, embryonic demise, fetal demise, incomplete miscarriage, ectopic pregnancy).
- Understand safety and efficacy of treatment options for EPL.
- Counsel patients about management options of EPL: expectant care, medication management, and uterine aspiration.
- Counsel patients about management options for second-trimester fetal demise: induction vs. D&E.
Articles
American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins—Gynecology. ACOG Practice Bulletin No. 200: Early Pregnancy Loss.
Obstet Gynecol
. 2018;132(5):e197-e207. doi:
10.1097/AOG.0000000000002899
Tarleton JL, Benson LS, Moayedi G, Trevino J, with the assistance of Leah Coplon, Anitra Beasley, and Elise Boos on behalf of the Society of Family Planning Clinical Affairs Committee. Society of Family Planning Clinical Recommendation: Medication management for early pregnancy loss.
Contraception
. 2025;144:110805. doi:
10.1016/j.contraception.2024.110805
Nippita S, Cansino C, Goldberg AB, et al. Society of Family Planning Clinical Recommendation: Management of undesired pregnancy of unknown location and abortion at less than 42 days of gestation.
Contraception
. Published online March 13, 2025:110865. doi:
10.1016/j.contraception.2025.110865
Rodgers SK, Horrow MM, Doubilet PM, et al. A Lexicon for First-Trimester US: Society of Radiologists in Ultrasound Consensus Conference Recommendations.
American Journal of Obstetrics and Gynecology
. 2025;232(1):1-16. doi:
10.1016/j.ajog.2024.07.038
Trending Topics
Judge-Golden C, Flink-Bochacki R. The Burden of Abortion Restrictions and Conservative Diagnostic Guidelines on Patient-Centered Care for Early Pregnancy Loss.
Obstet Gynecol
. 2021;138(3):467-471. doi:
10.1097/AOG.0000000000004509
Supplemental Resources
Early Pregnancy Loss. Innovating Education in Reproductive Health. Accessed April 2025.
Mehta TS. Ultrasonography of Pregnancy of Unknown Location. Accessed April 2025.
https://www.uptodate.com/contents/ultrasonography-of-pregnancy-of-unknown-location?search=pregnancy%20unknown%20location&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1
Tulandi T. Ectopic Pregnancy: Clinical Manifestations and Diagnosis. Accessed April 2025.
https://www.uptodate.com/contents/ectopic-pregnancy-clinical-manifestations-and-diagnosis?search=ectopic&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1